Journal of Enzymes
An international open access, peer-reviewed platform advancing molecular understanding of enzyme structure, function, regulation, and biotechnological applications.
Advancing Enzyme Science Discovery
Journal of Enzymes (JEN) (ISSN 2690-4829) serves as a dedicated forum for enzymology research spanning molecular mechanisms, protein engineering, catalytic pathways, and biotechnology innovation. As a COPE-aligned, open access journal backed by Open Access Pub, JEN facilitates rapid dissemination of high-quality scholarship.
Our editorial mission centers on scientific rigor through expert peer review, open accessibility via Creative Commons Attribution (CC BY 4.0) licensing, and global collaboration connecting biochemists, molecular biologists, structural scientists, and bioengineers worldwide.
JEN provides a multidisciplinary platform for enzyme-centered research that bridges fundamental biochemistry with applied biotechnology. Our scope encompasses molecular architecture, catalytic mechanisms, regulatory networks, and translational applications across diverse biological and industrial contexts.
Clinical/Medical Enzymology
Clinical studies clarifying enzyme biomarkers, diagnostic workflows, and enzyme-based interventions in human disease. Research on enzyme deficiencies, enzyme replacement therapy, enzymatic drug metabolism, and the role of enzymes in inflammation, oncology, metabolic disorders, and rare genetic conditions.
Systems-Level / Pathway Enzymology
Research mapping enzyme networks, pathway dynamics, and multi-enzyme regulation at cellular or organismal scale. Topics include pathway rewiring, metabolic control analysis, enzyme co-factor balance, and systems biology approaches linking enzyme function to phenotype.
Therapeutic Enzyme Modalities
Studies exploring therapeutic enzymes including enzyme replacement, enzyme prodrug activation, enzyme-based biologics, and enzyme-mediated detoxification. Innovations in delivery systems, stability engineering, and clinical pharmacology improving safety and efficacy.
Enzyme Structure and Dynamics
X-ray crystallography, cryo-EM, NMR spectroscopy, molecular modeling, protein folding, active site architecture, conformational changes, and structure-function relationships.
Catalytic Mechanisms
Reaction kinetics, substrate specificity, transition state analysis, cofactor interactions, allosteric regulation, enzyme inhibition, and mechanistic pathway elucidation.
Enzyme Engineering and Design
Directed evolution, rational design, site-directed mutagenesis, protein fusion strategies, stability enhancement, activity optimization, and novel catalyst development.
Industrial Biocatalysis
Enzyme production systems, bioreactor optimization, immobilization techniques, thermostability engineering, organic synthesis applications, and green chemistry.
Computational Enzymology
Molecular dynamics simulations, quantum mechanics/molecular mechanics (QM/MM), docking studies, structure prediction, and in silico screening.
Enzyme Kinetics and Assays
Steady-state kinetics, pre-steady-state analysis, single-molecule studies, high-throughput screening, fluorescence-based assays, and analytical methodology.
- Specialized Focus: Dedicated platform for enzyme research ensures your work reaches targeted audiences of biochemists, structural biologists, and bioengineers.
- Rigorous Peer Review: Expert evaluation by specialists in enzyme mechanisms, protein structure, and biotechnology ensures scientific accuracy and methodological rigor.
- Rapid Publication: Streamlined editorial workflows deliver first decisions within 21 days, with acceptance-to-publication turnaround under 5 days.
- Open Access Advantage: CC BY 4.0 licensing maximizes visibility and enables unrestricted sharing, citation, and downstream application.
- Global Discoverability: Indexed in Google Scholar, Crossref, and specialty databases; DOI assignment ensures permanent citation tracking.
- No Length Restrictions: Comprehensive reporting of experimental details, structural data, kinetic parameters, and supplementary materials supported.
- Interdisciplinary Integration: Bridges molecular biology, structural biochemistry, computational science, and biotechnology applications.
Journal of Enzymes offers flexible submission options designed to accommodate diverse author preferences and institutional workflows. All methods integrate seamlessly with our editorial management system.
Online Form
No login required. Direct upload via intuitive web interface with immediate confirmation and tracking capabilities.
Email Submission
Send manuscripts directly to our editorial office with cover letter and supporting files for rapid processing.
Manuscript Zone
Full-featured portal with account-based tracking, revision management, and communication history.
Submission Requirements: Manuscripts should follow our Instructions for Authors, including structured abstracts, methodology transparency, data availability statements, and compliance with ethical standards for protein expression, recombinant systems, or organism-based studies. Authors are encouraged to deposit structural coordinates in PDB and sequence data in appropriate repositories.
Editorial Leadership
JEN's editorial board comprises internationally recognized experts in structural biology, enzyme kinetics, protein engineering, and biocatalysis. Our editors ensure manuscripts receive knowledgeable evaluation focused on mechanistic insight, experimental rigor, and reproducibility.
Associate editors specialize in diverse enzyme families and applications, providing focused oversight for manuscripts within their domains of expertise.
Join Our Editorial Community
We welcome scientists with expertise in enzymology, biochemistry, molecular biology, or related fields to join our editorial and reviewer networks. Editorial board members shape journal direction, evaluate manuscripts, and contribute to special issues.
Reviewers benefit from recognition, certificates, and priority consideration for editorial roles. Learn more about opportunities and expectations through our editorial board page.
Journal of Enzymes adheres to COPE guidelines and maintains rigorous standards for research integrity, authorship attribution, conflict of interest disclosure, and data transparency. All submissions undergo similarity screening, and ethical compliance is verified before review begins.
Author Responsibilities: Manuscripts must represent original work not under consideration elsewhere. Authors must disclose funding sources, competing interests, and contributions using CRediT taxonomy. Protein sequences, structural data, and kinetic parameters should be deposited in appropriate public repositories.
Peer Review Process: Single-blind review by specialists ensures fair evaluation. Authors may request double-blind review when appropriate. Reviewers assess experimental design, analytical methods, data interpretation, and reproducibility while providing constructive feedback.
Consult our comprehensive editorial policies for detailed guidance on authorship, conflicts of interest, corrections, and misconduct investigation procedures.
"I cannot say enough about how good my experience working with OAP was. Submission is easy, and the editorial staff responds promptly and professionally. The entire process from submission to PDF was completed in 60 days rather than months."
"My experience with JEN is that JEN is a good scientific journal in the field of life science. The peer review process confirms the validity of science reported in the journal at a high standard. Editors treat peer review as an integral part of scientific publishing. The qualities of manuscript processing are professional. I will be very glad to recommend the journal to other potential authors."
Advance Enzyme Science with JEN
Whether you investigate catalytic mechanisms, engineer novel biocatalysts, solve enzyme structures, or develop biotechnology applications, Journal of Enzymes provides a rigorous, responsive publication platform that amplifies your research impact.
Contact Journal of Enzymes: For inquiries about manuscript suitability, submission procedures, editorial board opportunities, or publication policies, contact our editorial office at [email protected]. We are committed to supporting authors through every stage of the publication process.
